Vitamin K

What is Vitamin K?

  • Vitamin K is a fat-soluble vitamin essential for blood clotting and bone health.

  • It comes in two primary forms: Vitamin K1 (phylloquinone), found in plants, and Vitamin K2 (menaquinone), produced by gut bacteria and found in fermented foods and animal products.

  • Vitamin K plays a key role in several body processes, making it a vital nutrient for overall health.

What does Vitamin K do in our body?

  • Blood clotting: Vitamin K is critical for producing proteins like prothrombin, which helps blood coagulate (clot) to prevent excessive bleeding.

  • Bone health: It helps activate osteocalcin, a protein that binds calcium to bones, supporting bone density and preventing fractures.

  • Heart health: Vitamin K prevents calcium buildup in the arteries, which lowers the risk of heart disease.

  • Brain function: There’s emerging research suggesting that Vitamin K may support cognitive function by protecting brain cells from oxidative stress.

Major Warning Signs of Vitamin K Deficiency

  • Excessive bruising: One of the first signs of deficiency, due to reduced blood clotting.

  • Frequent nosebleeds: This happens when clotting factors are insufficient.

  • Heavy menstrual bleeding: For women, prolonged or heavy periods can be a sign.

  • Bleeding gums: A noticeable symptom when brushing or flossing.

  • Blood in urine or stools: A more severe sign that indicates internal bleeding.

Other Deficiency Symptoms in Vitamin K

  • Weak bones: Due to insufficient calcium binding to the bone matrix.

  • Osteoporosis: A long-term deficiency can lead to low bone mineral density.

  • Heart problems: Increased risk of arterial calcification.

  • Slow wound healing: Since clotting is delayed, even minor cuts may take longer to heal.

Vitamin K Deficiency in the Immune System

  • Weakened immune response: Vitamin K supports certain proteins that can influence inflammation and immune health. A deficiency may lead to impaired immune defense.

Vitamin K Deficiency in the Cardiovascular System

  • Arterial calcification: Without Vitamin K, calcium may build up in the arteries, increasing the risk of heart disease.

  • Blood vessel damage: Vitamin K helps maintain flexible and strong blood vessels, so a deficiency may lead to weakened blood vessel walls.

Vitamin K Deficiency in the Integumentary System

  • Skin bruising: The skin may bruise easily because of impaired clotting.

  • Wound healing issues: Vitamin K deficiency can delay the skin’s natural healing process, causing prolonged bleeding and scarring.

Vitamin K Deficiency in the Lymphatic System

  • Lymphatic system function: While direct evidence is limited, Vitamin K is involved in the regulation of proteins that impact inflammation, potentially affecting lymphatic drainage and immune responses.

Vitamin K Deficiency in the Endocrine System

  • Hormonal balance: Vitamin K plays a lesser-known role in regulating insulin sensitivity, which may impact hormone regulation if deficient.

Vitamin K Deficiency in the Muscular System

  • Muscle pain and weakness: Vitamin K helps with bone mineralization, which indirectly affects muscle function. Deficiency may lead to cramps or muscle weakness, due to poor bone structure.

Vitamin K Deficiency in the Digestive System

  • Fat malabsorption issues: Since Vitamin K is fat-soluble, conditions like Crohn’s or celiac disease, which interfere with fat absorption, can exacerbate deficiency.

  • Gut health: Reduced Vitamin K2, which is produced by gut bacteria, can lead to digestive imbalance and poor nutrient absorption.

Vitamin K Deficiency in the Nervous System

  • Neurological issues: Though less studied, some research suggests Vitamin K might protect brain cells from oxidative stress, so a deficiency may impact brain health and cognitive functions.

Vitamin K Deficiency in the Skeletal System

  • Osteopenia and osteoporosis: Vitamin K is essential for bone mineralization. Its deficiency can cause weak bones and an increased risk of fractures.

  • Impaired calcium utilization: Without Vitamin K, calcium cannot properly bind to bone tissue, leading to low bone density.

Vitamin K Deficiency in the Thyroid Pathway

  • Impact on thyroid function: Although Vitamin K does not directly affect the thyroid, its role in calcium regulation can influence overall metabolic health, indirectly affecting thyroid hormone metabolism.

Vitamin K Deficiency in the Liver

  • Reduced production of clotting factors: The liver depends on Vitamin K to produce clotting proteins. Deficiency can lead to impaired liver function and a heightened risk of internal bleeding.

Causes of Vitamin K Deficiency

  • Poor dietary intake: Not consuming enough leafy greens or fermented foods can lead to a deficiency.

  • Fat malabsorption: Conditions like cystic fibrosis, Crohn’s disease, or celiac disease impair the body’s ability to absorb Vitamin K.

  • Antibiotic use: Long-term antibiotic use can kill gut bacteria, which produce Vitamin K2.

  • Liver disease: The liver’s role in producing clotting factors is dependent on Vitamin K.

Physical Ailments Requiring more Vitamin K

  • Bone fractures: Increased intake of Vitamin K can aid in faster recovery by supporting bone health.

  • Blood clotting disorders: Those with clotting issues may benefit from higher Vitamin K levels.

  • Heart disease: Vitamin K supplementation may help reduce arterial calcification.

Medications that Deplete Vitamin K

  • Antibiotics: Long-term use reduces gut bacteria that produce Vitamin K.

  • Blood thinners: Medications like warfarin work by blocking Vitamin K's function in the clotting process, making it essential to monitor Vitamin K levels when using these drugs.

  • Cholesterol-lowering drugs: Statins can interfere with fat absorption, indirectly reducing Vitamin K absorption.

Natural Supplements that Deplete Vitamin K

  • High doses of vitamin E: Large amounts of vitamin E can interfere with vitamin K absorption and increase bleeding risk.

Heavy Metals that Deplete Vitamin K

  • Lead and mercury: Heavy metals can interfere with nutrient absorption, including Vitamin K, by damaging gut health and overall nutrient assimilation.

Testing Vitamin K

  • Prothrombin time (PT): This blood test measures how long it takes for blood to clot. Longer clotting times may indicate a Vitamin K deficiency.

  • Serum Vitamin K levels: Blood tests can directly measure Vitamin K levels, though these are less commonly done.

Daily Requirements of Vitamin K

  • Adult men: 120 micrograms/day

  • Adult women: 90 micrograms/day

  • Children and adolescents: Varying amounts depending on age, ranging from 30-75 micrograms/day.

Co-Factors Required for Vitamin K Absorption

  • Dietary fat: Vitamin K is fat-soluble, so it needs to be consumed with healthy fats for proper absorption.

  • Bile acids: These are produced by the liver and help emulsify fats to enhance Vitamin K absorption.

Foods high in Vitamin K

  • Leafy greens: Spinach, kale, Swiss chard, and collard greens are rich in Vitamin K1.

  • Fermented foods: Natto (fermented soybeans) is an excellent source of Vitamin K2.

  • Animal products: Liver, egg yolks, and cheese are high in Vitamin K2.

  • Herbs: Parsley, basil, and cilantro provide smaller amounts of Vitamin K.

Things that affect the amount of Vitamin K in our food

  • Storage: Prolonged storage or freezing can decrease Vitamin K content in foods.

  • Cooking methods: Boiling and overcooking can reduce Vitamin K levels in leafy greens, so light steaming or eating raw is ideal.

Other Random Information about Vitamin K

  • Gut bacteria production: Healthy gut flora produces Vitamin K2, so supporting gut health with probiotics can help maintain adequate levels.

  • Newborns and Vitamin K: Newborns are often given a Vitamin K shot to prevent bleeding, as they have low levels at birth.

  • Synergy with Vitamin D: Vitamin K works with Vitamin D to ensure calcium is directed to bones instead of arteries.

Final Thoughts…

  • I went to a low carb doctor recently and he told me that Vitamin D gets calcium into the bones, but Vitamin K keeps it there, so I have been using a Vit D & Vit K2 Spray in my mouth everyday. It’s super easy and I have actually noticed a difference in hair loss since taking it. Here is a similar one from iHerb if you are interested in testing it out.

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